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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC16 All Species: 18.18
Human Site: T589 Identified Species: 26.67
UniProt: Q13042 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13042 NP_001072113.1 620 71656 T589 P L E T S R K T P D S R P S L
Chimpanzee Pan troglodytes XP_001141335 657 75449 T626 P L E T S R K T P D S R P S L
Rhesus Macaque Macaca mulatta XP_001089625 620 71585 T589 P L E T S R K T P D S R P S L
Dog Lupus familis XP_848577 620 71476 T589 P L E T S R K T P D P R P S L
Cat Felis silvestris
Mouse Mus musculus Q8R349 620 71442 A589 P L Q N S T K A P E S R P N L
Rat Rattus norvegicus NP_001019915 620 71343 T589 P L E N A T K T P E S R P S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513048 324 37070 A294 S H P T R K A A D P R P P L E
Chicken Gallus gallus NP_001006265 624 72618 R591 T L E T S H Q R T N T D T S R
Frog Xenopus laevis NP_001087093 621 71792 L587 A L E T S N L L P K S S D T R
Zebra Danio Brachydanio rerio NP_001032466 616 70436 K586 T P S F N A D K Q T D A F Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623316 640 73022 N600 S G W G E S S N K A D D D T A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203133 551 62760 L351 G L T K N F K L A D K F F S Q
Poplar Tree Populus trichocarpa XP_002331799 542 62607 L512 Y H L Q A L W L K P D D Q F C
Maize Zea mays NP_001141501 580 66070 A549 A I N Y Y H K A L W L K P D D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_565188 543 61743 L513 Y Y H K A L W L K P D D Q F C
Baker's Yeast Sacchar. cerevisiae P09798 840 94974 T803 N M A K R L R T Q K E I F D Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 99.3 97.9 N.A. 95.4 95.9 N.A. 48.2 91.5 88.8 79.1 N.A. N.A. 49.6 N.A. 49
Protein Similarity: 100 94.3 99.6 98.5 N.A. 97.9 98 N.A. 50.1 95.8 95.8 87.9 N.A. N.A. 68.1 N.A. 66.7
P-Site Identity: 100 100 100 93.3 N.A. 60 73.3 N.A. 13.3 33.3 40 0 N.A. N.A. 0 N.A. 26.6
P-Site Similarity: 100 100 100 93.3 N.A. 80 86.6 N.A. 20 53.3 46.6 6.6 N.A. N.A. 6.6 N.A. 33.3
Percent
Protein Identity: 35.8 36.9 N.A. 38.2 23.8 N.A.
Protein Similarity: 52.1 54.6 N.A. 54.3 41.5 N.A.
P-Site Identity: 0 13.3 N.A. 0 6.6 N.A.
P-Site Similarity: 6.6 26.6 N.A. 6.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 7 0 19 7 7 19 7 7 0 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % C
% Asp: 0 0 0 0 0 0 7 0 7 32 25 25 13 13 7 % D
% Glu: 0 0 44 0 7 0 0 0 0 13 7 0 0 0 7 % E
% Phe: 0 0 0 7 0 7 0 0 0 0 0 7 19 13 0 % F
% Gly: 7 7 0 7 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 13 7 0 0 13 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % I
% Lys: 0 0 0 19 0 7 50 7 19 13 7 7 0 0 0 % K
% Leu: 0 57 7 0 0 19 7 25 7 0 7 0 0 7 38 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 7 13 13 7 0 7 0 7 0 0 0 7 0 % N
% Pro: 38 7 7 0 0 0 0 0 44 19 7 7 50 0 0 % P
% Gln: 0 0 7 7 0 0 7 0 13 0 0 0 13 7 13 % Q
% Arg: 0 0 0 0 13 25 7 7 0 0 7 38 0 0 19 % R
% Ser: 13 0 7 0 44 7 7 0 0 0 38 7 0 44 0 % S
% Thr: 13 0 7 44 0 13 0 38 7 7 7 0 7 13 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 7 0 0 0 13 0 0 7 0 0 0 0 0 % W
% Tyr: 13 7 0 7 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _